Mass Cytometry

Combining the best in Flow Cytometry & Mass Spectrometry - With Single Cell Resolution

The Lunarion® 
Next Resolution in Medicine

The Lunarion®
From Polaris Biology

The Lunarion® from Polaris Biology is a state-of-the-art mass cytometry platform combining the high-dimensional power of time-of-flight mass spectrometry with the versatility of flow cytometry. Designed for both research and clinical use, it delivers unparalleled resolution, sensitivity, and throughput for comprehensive single-cell proteomic profiling.

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The Science Behind Lunarion®


The Breakthrough Single-Cell Technology

Studying Single Cells?

How Lunarion® Makes It Possible

In complex tissues, each cell type plays a unique role — and subtle changes at the single-cell level can define health, disease progression, or therapeutic response. Bulk analysis masks this diversity, averaging signals and overlooking rare but critical cell populations. Single-cell analysis uncovers this hidden heterogeneity, revealing cell-specific protein expression, functional states, and interactions that drive biological outcomes.

From Isotope Tagging to Precision Detection

How Lunarion® Makes It Possible

Mass cytometry uses stable metal isotopes to tag antibodies, replacing traditional fluorophores and eliminating issues like spectral overlap and autofluorescence. In the Lunarion® system, each cell passes through an inductively coupled plasma (ICP), where the metal tags are ionized and precisely measured by a high-resolution time-of-flight (TOF) mass spectrometer. This allows simultaneous detection of up to 140 parameters per cell with exceptional accuracy and minimal signal spillover. The result is a true high-dimensional fingerprint of every single cell, enabling researchers to deeply profile immune landscapes, identify rare populations, and discover novel biomarkers — all in one efficient assay.

Streamlined Workflow, Deeper Insights

Automated Sample Introduction

Compatible with cytometry tubes, 96-well and deep-well plates, with built-in cooling for sample integrity.
Delivers consistent, high-throughput acquisition while minimizing manual handling.

Automated Instrument Cleaning

Unattended fluidics maintenance ensures system reliability and prevents clogging.
Fully integrated cleaning and waste management for hassle-free daily operation.


Over 300 Unique Antibodies

Extensive library of validated metal-tagged antibodies for diverse research applications.
Supports ready-to-use panels or fully customizable designs for targeted single-cell studies.


Specifications

The Lunarion®Polaris Biology Mass Cytometry PanelsImmune-Oncology PanelsImmune Landscape Phenotyping PanelsApplication-Focused Mass Cytometry Panels

The Lunarion®

Info

Specifications

Dimensions (LxWxH)

1243 mm x 752 mm x 992 mm

Weight

360 kg

Resolution

800-1200

Sample Introduction

Automatic

Sample Size

30 uL - 4.5 mL

Flow Rate

80 uL/min

Average Event Rate

500-1,000 cells/s

Maximum Event Rate

2,000 cells/s

Calibration

Automatic

Dynamic Range

4.5 Orders of Magnitude

Channels

141

Mass Range

70-210 amu

Replicate Sample CV

<2%

TOF Pulser Frequency

> 125KHz

ADC Conversion Rate

> 2Gs/s

Operating System

Windows

UI Language

English, Chinese


Polaris Biology Mass Cytometry Panels


Info


Immune-Oncology Panels

The Polaris Biology Immune-Oncology Panels are developed to support advanced tumour immunology and immunotherapy research through simultaneous profiling of immune checkpoint molecules, activation markers, suppressive immune populations, and tumour-associated immune phenotypes. These panels allow researchers to investigate immune exhaustion, checkpoint regulation, CAR-T responses, T cell functionality, and tumour microenvironment dynamics with minimal signal spillover and high multiplexing capability. Suitable for both human and mouse studies, the panels accelerate biomarker discovery, translational oncology research, and immunotherapy development workflows.    

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Available Panels

  • Human Immune-Oncology Panel (35-marker)
  • Mouse Immune-Oncology Panel (27-marker)


Immune Landscape Phenotyping Panels

Polaris Biology Immune Landscape Phenotyping Panels are designed for comprehensive high-dimensional immune profiling across human and mouse research models. These validated mass cytometry panels enable deep characterization of lymphoid and myeloid populations, immune activation states, memory phenotypes, exhaustion markers, and functional immune heterogeneity in a single experiment. Optimized for the Lunarion Mass Cytometry System, the panels support streamlined workflows for PBMC analysis, translational immunology, tumour microenvironment studies, infectious disease research, and systems immunology applications.    


Available Panels

  • Human Immune Landscape Phenotyping Panel (30-marker)
  • Mouse Immune Landscape Phenotyping Panel (31-marker)


Application-Focused Mass Cytometry Panels

Beyond core immunophenotyping workflows, Polaris Biology also offers a growing portfolio of application-focused mass cytometry panels tailored for specific disease areas and translational research applications. These ready-to-use solutions are optimized for tumour microenvironment profiling, CAR-T characterization, infectious disease research, autoimmunity, and organ-specific immune landscape analysis across both human and mouse models.  


Featured Application Panels

  • Human Lung Cancer Lymphocyte Phenotyping Solution
  • Human Lung Cancer Myeloid Cell Phenotyping Solution
  • Human Breast Cancer Immunophenotyping Solution
  • Human Breast TME Immunophenotyping Solution
  • Human Colorectal Cancer Immunophenotyping Solution
  • Human Colorectal TME Immunophenotyping Solution
  • Human Kidney Cancer Lymphocyte Phenotyping Solution
  • Human Kidney Cancer Myeloid Cell Phenotyping Solution
  • Human Hepatic Cancer Immunophenotyping Solution
  • Human CAR-T Phenotyping Landscape Solution
  • Human CAR-T Functional Landscape Solution
  • Human Infectious Immunology Solution
  • Human Autoimmunology Solution
  • Mouse PBMC Phenotyping Solution
  • Mouse Sp/LN Phenotyping Landscape Solution



From Flow to Mass: The Next Leap in Single-Cell Analysis

Hear what other Researchers say

Next Resolution in Medicine!

We look forward to learn more about your research scope and how we may provide support for high precision, quantitative and ultra-sensitive applications


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