One Tube, Zero Errors: Try the NZY RT SuperMix 5×

Get Your Sampler Today

Reverse transcription is one of the most error-prone steps in any qPCR workflow. Multiple pipetting steps, reagent exposure, and the ever-present threat of RNase contamination all introduce variability that researchers do not need.


If you want a cleaner, more reproducible start to every expression experiment, NZY RT SuperMix 5× was engineered precisely for that purpose — and we are now offering limited sampler units for researchers who want to validate this premium Portugal-made mix in their own RT-qPCR workflow.


🔗 Request your sampler (while stocks last):

https://www.darwinscience.com/contactus


Why One-Tube RT Makes a Difference


Traditional RT setups require mixing multiple components — RT enzyme, buffer, dNTPs, RNase inhibitor, primers — each introducing more chances for pipetting error and contamination.


The NZY RT SuperMix 5× consolidates everything into one ready-to-use master mix that contains:

  • RNase-H minus reverse transcriptase
  • RNase inhibitor
  • dNTPs
  • Optimized RT buffer
  • Random hexamers + oligo(dT)₁₈ priming system
  • Stabilizers for consistent performance

This single-tube configuration dramatically reduces hands-on burden while protecting RNA integrity — especially important for delicate or low-abundance samples.


Fast, Precise, and Built for Modern qPCR Workflows


10-Minute RT Reaction


A complete first-strand cDNA synthesis is done in as fast as 10 minutes at 50–55 °C, making it ideal for high-throughput labs or rapid turnaround studies.


Higher RNA Input Flexibility


The 5× format allows you to add more RNA per reaction, supporting a wide input range from 10 pg to 5 µg.


This is particularly valuable for:

  • Low-input clinical or environmental RNA
  • Rare transcripts
  • High-sensitivity gene expression assays


Consistent, Contamination-Resistant Performance


By reducing pipetting steps, you naturally minimize:

  • Aerosol contamination risk
  • Cross-sample contamination
  • Variability between technicians
  • RNase exposure
  • Setup time


It’s a straightforward way to tighten workflow precision — without changing your qPCR pipeline.


Ideal for All RT-qPCR Applications


The NZY RT SuperMix 5× is validated for downstream use in:

  • Real-time PCR
  • Gene expression studies
  • RNA quantification
  • General PCR workflows


It is available in two pack sizes:

🔹 50 reactions

🔹 250 reactions


📦 Product page:

https://www.darwinscience.com/shop/nzy-rt-supermix-5x-548145#attr=1654


Sampling Campaign: Try It Before You Switch


We are running a sampling campaign from now until 24 March 2025, enabling researchers to test the NZY RT SuperMix 5× directly within their lab’s real-time PCR workflow.


If you value clean setup, reproducibility, and high-quality cDNA — this is the perfect opportunity to evaluate it firsthand.


👉 🔗 Request your sampler (while stocks last):

https://www.darwinscience.com/contactus